Gaur et al.

Angiotensin Receptor Blocker work by inhibition ofAngiotensin-II by competitive

blocking the angiotensin-I receptor and it reduce adverse effect and possibly

improve clinical efficacy.

Figure 1

Blood vessels narrows because of entry of Angiotensin-II in to the blood

stream which leads to increase of blood pressure of the body. It also activates

a hormone which causes the water retention of body. ARBs having a very high

affinity towards the AT-1 Receptor but negligible affinity towards AT-2 receptor.

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International Journal of Bioinformatics and Biological Sciences : v.2 n.3&4. Dec. 2014