Perspectives into probiotics- From phenotyping to pyrosequencing

Epilogue

Department of Dairy Microbiology isȱtheȱfirstȱinȱIndiaȱtoȱhaveȱdepositedȱ

Indigenous probiotic culture in an International culture repository, carry

out the whole genome sequencing of the culture and license the culture for

commercial application in Indian market. We have backed the claims of our

indigenous strain with clinical and metagenomics studies. Understanding

the role of indigenous intestinal bacteria and their ecological interactions

play in human health and disease based on epidemiological, intervention

and mechanistic studies will facilitate the optimization of integrated

dietaryȱ strategiesȱ toȱ efficientlyȱ modulateȱ theȱ humanȱ gutȱ microbiome,ȱ

leading to improvements in nutrition and clinical practice. Additionally,

these studies need to be conceptualized with ‘Indian’ as the focal point.

Although such studies will be challenging they will bring understanding

thatȱisȱrelevantȱtoȱtheȱhealthȱofȱIndians.ȱOurȱongoingȱeffortsȱareȱdirectedȱtoȱ

assess host gene-diet interactions within the context of the structure and

operations of gut microbial communities. The department fosters a vision

to play a pioneering role in tailored probiotic therapy.

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