Vohra et al.

Muredda M., Nunoya K., Burtch-Wright R.A., Kurz E.U., Cole

Schweizer M., Roder K., Zhang L. and Wolf S.S. 2002.

S.P. & Deeley R.G. 2003. Cloning and characterization of

Transcription factors acting on the promoter of the rat fatty

the murine and rat Mrp1 promoter regions. Mol. Pharm. 64 :

acid synthase gene. Biochem. Soci. Trans. 30 : 1070–2.

1259–69.

Semenkovich C.F., Coleman T. and Goforth R. 1993. Physiologic

Oh, D., Y. Lee, B. La, J. Yeo, E. Chung, Y. Kim and C. Lee.

concentrations of glucose regulate fatty acid synthase activity

2011. Fatty acid composition of beef is associated with

in HepG2 cells by mediating fatty acid synthase mRNA

exonic nucleotide variants of the gene encoding FASN. Mol.

stability. J. Bio. Chem. 268 : 6961–70.

Biol. Rep. 39(4) : 4083-4090.

Smith, S. 1994. The animal fatty acid synthase: one gene, one

Roy, R., Ordovas, L., Zaragoza, P., Romero, A., Moreno,

polypeptide, seven enzymes. FASEB J. 8 : 1248–1259.

C., Altarriba, J. and Rodellar, C. 2006. Association of

Vázquez, M.J., Leavens, W., Liu, R., Rodríguez, B., Read, M.,

polymorphisms in the bovine FASN gene with milk-fat

Richards, S., Winegar, D., Domínguez, J.M. 2008. Discovery

content. Anim. Genet. 37(3) : 215-218.

of GSK837149A, an inhibitor of human fatty acid synthase

Roy, R., Gautier, M., Hayes, H., Laurent, P., Eggen, A., Osta, R.,

targeting the beta-ketoacyl reductase reaction. FEBS J. 275 :

Zaragoza, P. and Rodellar C. 2001. Assignment of fatty acid

1556–1567.

sythase (FASN) gene to bovine chromosome 19 (19q22) by

Vohra, V. and Chakravarty, A.K. 2011. Sustainable breeding in

in situhybridization and confirmation by hybrid somatic cell

cattle and buffalo. First edn. Satish Serial Publishing House,

mapping. Cytogenet. Cell Genet. 93(1-2) : 141-142.

New Delhi, India

Schennink, A., Bovenhuis, H., Leon-Kloosterziel, K.M., Van

Wakil S.J., Stoops J.K. and Joshi V.C. 1983. Fatty acid synthesis

Arendonk, J.A.M and Visker M.H.P.W. 2009. Effect of

and its regulation. Annual Review of Biochemistry 52 : 537–

polymorphisms in the FASN, OLR1, PPARGC1A, PRL and

79.

STAT5A genes on bovine milk-fat composition. Anim. Genet.

40(6) : 909-916.

Zhang, S., Knight, T.J., Reecy J.M. and Beitz, D.C. 2008. DNA

polymorphisms in bovine fatty acid synthase are associated

with beef fatty acid composition. Anim. Genet. 39(1) : 62-70.

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